Among these, (i) a Belgian patient with a very early onset FTLD (49 years) carrying two potentially damaging compound heterozygous variants in VPS52, a subunit of the Golgi-associated retrograde protein complex (interacting with the PD-associated LRRK2) which is involved in retrograde transport of early and late endosomes to the Golgi [53]; (ii) three patients carrying the ultrarare ABCA2 p.H1449P variant, which was found to be nominally associated with disease, but this did not survive after multiple test correction. Here, LRRK2 is linked to Parkinson disease.