Specifically, we found three previously reported variants in the sortilin-related receptor 1 (SORL1) gene: the SORL1 p.N1246K heterozygous variant, previously described as an AD risk factor [22,23], was found in a familial AD patient; the SORL1 p.N371T and p.D2065V heterozygous variants, previously described in two AD patients of North European ancestry [24], were found in an early onset AD and in an FTLD patient and in n = 4 AD, n = 2 DLB and n = 6 FTLD patients, respectively (Table 4). The gene discussed is SORL1; the disease is Alzheimer disease.