ABCA2 and Parkinson disease: Among these, (i) a Belgian patient with a very early onset FTLD (49 years) carrying two potentially damaging compound heterozygous variants in VPS52, a subunit of the Golgi-associated retrograde protein complex (interacting with the PD-associated LRRK2) which is involved in retrograde transport of early and late endosomes to the Golgi [53]; (ii) three patients carrying the ultrarare ABCA2 p.H1449P variant, which was found to be nominally associated with disease, but this did not survive after multiple test correction.