The SORL1 p.N1246K variant, previously described as an AD risk factor [22,23], was found in a familial AD patient; the SORL1 p.N371T and the SORL1 p.D2065V variants, previously described in two unrelated AD patients of North European ancestry [24], were found in our dataset in AD, DLB and FTLD patients. Here, SORL1 is linked to Alzheimer disease.