Detection of PCA3 and TMPRSS2:ERG mRNA in EVs derived from readily obtained EPS urine constitute a viable clinical application for PCa screening [80].In order to evaluate available omics data regarding PCa and EVs we performed a detailed PubMed search with the terms displayed in Table S1 (performed in September, 2021). Here, TMPRSS2 is linked to posterior cortical atrophy.