AKT1 and squamous cell intraepithelial neoplasia: The strong activation of AKT and MAPK, and the cross-talks between these signaling pathways, rapidly induce the EMT pro-invasive phenotype in cervical epithelial cells, thereby promoting SIL and its progression to invasive SCC [9,17,79,80,81,82,83,84,85,87,185,186,187].