Intriguingly, overexpression of DNAJA3/Tid1 enhances mitochondrial translocation of multiple mutp53 (R175H, L194F, R273H, E285K) in several breast cancer and glioblastoma cell lines, resulting in increased mitochondrial apoptosis regardless of the presence of hypoxic stress [68]. This evidence concerns the gene DNAJA3 and glioblastoma.