Importantly, some DNAJB proteins, including DNAJB1/HDJ1, DNAJB4/HLJ1, DNAJB6/MRJ, DNAJB8, DNAJB9/MDG1/ERdj4, DNAJB11/ERdj3/HEDJ, and DNAJB12, are implicated in cancer progression [72,115,116,117,118,119,120,121,122,123,124,125,126,127]. This evidence concerns the gene DNAJB8 and cancer.