In humans, mild glucosuria (<10 g/1.73 m2/24 h) tends to be associated with heterozygous SLC5A2, while severe glucosuria (≥10 g/1.73 m2/24 h) is experienced by individuals with homozygosity or compound heterozygosity for SGLT2 mutations [65]. This evidence concerns the gene SLC5A2 and Glycosuria.