On the other hand, the Sengers syndrome phenotype overlaps with those of protein biogenesis disorders, such as mutation in the mitochondrial adenine nucleotide translocator (ANT) [35], and of diseases of lipid metabolism, such as Barth syndrome [36]. Here, SLC25A4 is linked to Congenital cataract - hypertrophic cardiomyopathy - mitochondrial myopathy.