mTOR regulates ribosomal protein S6 kinase 1 (S6K1; p70S6K) and eukaryotic initiation factor 4E (eIF4E)-binding protein 1 (4EBP1), and their activation and phosphorylation by mTOR promote protein synthesis and tumor growth [30]. The gene discussed is EIF4EBP1; the disease is neoplasm.