In order to correlate lymphoangiogenesis with the melanoma dissemination in our animal model, the lungs, livers, kidneys, and spleens of mice were collected and examined with an antibody cocktail of anti-melanosome (HMB45), anti-MART-1/melan A (A103), and anti-tyrosinase (T311) mouse monoclonal antibodies. Here, PMEL is linked to melanoma.