AKT1 and non-Hodgkin lymphoma: Kruskal–Wallis analysis revealed that the staining intensity of S473-phosphorylated Akt normalized by the nuclei intensity value was significantly increased in pSS patients without or with NHL compared to sicca-controls (mean intensity score 8.60, 7.45, and 0.53 in pSS patients without NHL, with NHL, and sicca-controls, respectively; statistical significance: p < 0.0001 for pSS patients without NHL vs. sicca-controls and p = 0.0026 for pSS patients with NHL vs. sicca-controls) (Figure 2A).