For instance, Wan et al. identified the acetylation of HOXB9 as an important post-translational modification which caused suppression of transcription of the HOXB9 target gene Jumonji domain-containing protein 6 (JMJD6), leading to the inhibition of tumour growth and the migration of lung adenocarcinoma cells, in vitro and in vivo [61]. Here, JMJD6 is linked to neoplasm.