EXOSC2 and retinitis pigmentosa: Given that mutations in pre-mRNA processing factors (PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, and RP9) have been linked to 15–20% of autosomal dominant retinitis pigmentosa, retinitis pigmentosa of EXOSC2-associated SHRF may be associated with misprocessing of pre-mRNAs and snRNAs [93].