Enhanced CCL20 activity may induce epidermal hyperplasia as well as the migration of chemokine receptor 6 (CCR6) positive Langerhans/Dendritic cells to the skin, which are crucial in the evolution of lymphoma cells as the activation of T-cell receptors is crucial for the malignant transformation of MF [18,103]. The gene discussed is CCL20; the disease is mycosis fungoides.