Indeed, the levels of sE-cadherin were positively correlated to s-creatinine, age, erythrocyte sedimentation rate, triglycerides, and elevated sE-cadherin levels detected in SLE patients with renal damage, suggesting a possible relationship between lipid metabolism and E-cadherin shedding in patients with SLE [120]. This evidence concerns the gene CDH1 and systemic lupus erythematosus.