LOX and cancer: Specifically, HT-1080 cells exposed to M2 macrophage-incubated iron oxide nanoparticles (5 nm) combined with LOX at pH 6.7 significantly suppressed cancer cell growth (28.4%) compared to the HT-1080 cells exposed to M2 macrophages treated with iron oxide nanoparticles (51.2%) or LOX (82.2%) at pH 6.7.