RRM2 and non-small cell lung carcinoma: In recent times, Zhang et al. discovered the link between ferroptosis-related genes and LUAD, a subtype of NSCLC, revealing the predictive significance of 15 ferroptosis genes (RELA, ACSL3, YWHAE, EIF2S1, CISD1, DDIT4, RRM2, PANX1, TLR4, ARNTL, LPIN1, HERPUD1, NCOA4, PEBP1, and GLS2) in clinical NSCLC patients.