Mutations in other genes such as epidermal growth factor receptor (EGFR), tumor protein p53 (TP53), MET proto-oncogene, receptor tyrosine kinase (MET) and loss of cyclin-dependent kinase inhibitor 2A (CDKN2A) were observed in MPNST [15]. Here, CDKN2A is linked to malignant peripheral nerve sheath tumor.