CORT and post-traumatic stress disorder: GCs are the mediators between PTSD-like anxiety symptoms and histological adrenal alterations, a relation that is supported by positive correlations between nucleus diameter in the zona fasciculata and CORT concentration in plasma and the adrenal glands, as well as between nucleus diameter in the zona intermedia and 11-desoxyCORT concentration in adrenals of PSS-exposed rats.