↓ L-687,414-induced hyperactivity (mouse) [111]↓ cocaine-induced hyperactivity, self-administration & relapse (mouse/rat) [110,111]↓ d-AMPH-induced hyperactivity in rats, no effect in mice [112]↓ mAMPH-induced hyperactivity and self-administration (rat) [112]↓ hyperactivity in DAT-KO mice and rats [109,113]↓ hyperactivity in NR1-KD mice [111]pro-cognitive effect in object retrieval tasks (monkey) [111]antidepressant-like effect in FST (rat) and differential reinforcement of low-rate behavior (monkey) [111]modest anxiolytic effect in SIH (mouse) [111]↓ haloperidol-induced catalepsy (rat) [111]. The gene discussed is SLC6A3; the disease is catalepsy.