MDM2 and congestive heart failure: In the CHF group, a significant decrease in the mRNA expression was observed for MURF1 (CHF: 0.18 ± 0.09, 10 w control: 0.30 ± 0.13, p = 0.03), ITCH (CHF: 0.03 ± 0.02, 10 w control: 0.07 ± 0.05, p = 0.02), CHIP (CHF: 0.11 ± 0.17, 10 w control: 0.32 ± 0.53, p < 0.01) and MDM2 (CHF: 0.26 ± 0.11, 10 w control: 0.46 ± 0.23, p = 0.03) (Figure 1).