USP19 and congestive heart failure: The DUB mRNA analysis expression revealed that USP19 expression was decreased in the acute MI group (acute MI: 0.12 ± 0.01, 3 d control: 0.31 ± 0.06, p < 0.01) and the CHF group (CHF: 0.15 ± 0.01, 10 w control: 0.35 ± 0.05, p < 0.01) (Figure 3A).