Ablation of a specific MMP can lead to compensatory effects, thus we next examined expression of Mmp3, which belongs to the stromelysin family, as well as examining MMP-10, Mmp2 and Mmp9, the two major MMP gelatinases that have been associated with DMD cardiomyopathy [12]. The gene discussed is MMP3; the disease is cardiomyopathy.