TGFB1 and breast carcinoma: Given the inhibitory effects of MDZ on the TGF-β-induced proliferation and EMT in A549 and MCF-7 cells, we were interested to elucidate whether MDZ also possessed such an inhibitory effects on metastatic cell line, such as MDA-MB-231 cells, which is known to be a triple-negative, basal-B type breast cancer cell [34,35].