Finally, human DLD-1 CRC cells were pretreated with vehicle (ethanol) or resveratrol (50 μM) for 1 h and then kept as control or treated with visfatin (50 ng/mL) for 1 h (p38 phosphorylation) and 12 h (TYMS expression and Sp1 transcriptional activation). The gene discussed is SP1; the disease is colorectal carcinoma.