it is overexpressed in patient metastatic tissues and cell linespositively correlated with its parental geneshigh level is correlated with the worst clinicopathologic features (with larger tumor dimension, higher level of AFP, advanced TNM stages, tumor microsatellite formation and venous invasion)SOX4 activates the AKR1B10P1 transcriptionpositive feedback between AKR1B10P1 and miR-138 by competing endogenous RNA (ceRNA) wayAKR1B10P1/miR-138/SOX4 axis promotes cell proliferation. This evidence concerns the gene AKR1B10P1 and neoplasm.