it is upregulated in patient samples and cell linesits expression is higher in high-grade glioma compared with low-grade glioma tissuesoverexpression of FTH1P3 promotes glioma cell proliferation and inhibits apoptosisFTH1P3 inhibits miR-224-5p expression, which in turn negatively regulates TPD52 expressionthe FTH1P3/miR-224-5p/TPD52 axis is responsible for glioma progression. Here, TPD52 is linked to central nervous system cancer.