it is upregulated in patient samples and cell linesknockdown of PDIA3P suppresses cell viability, promotes apoptosis, and inhibits migration and invasionPDIA3P is negatively regulates miR-183 and influencing its target ITGB1,thus inducing the activation of FAK/PI3K/AKT/β-catenin signals and influencing tumor growth and metastasis. The gene discussed is PDIA3P1; the disease is neoplasm.