it is upregulated in patient sampleshigher expression is connected with shorter survivalexpression level of RPSAP52 is positively correlated with TGF-β1overexpression of RPSAP52 and TGF-β1 leads to increased and silencing of RPSAP52 to decreased CD133+ cells (phenotype of cancer initiating cells). Here, PROM1 is linked to cancer.