it is upregulated in patient samplesshortens the metaphase to anaphase transition in mitosis, increases cell viability after cisplatin or paclitaxel treatment, facilitates tumor growthassociated with a poor survival rate of patients who received chemotherapyPTTG3P interacts with the transcription factor FOXM1 to regulate the transcriptional activation of BUB1Bknockdown of PTTG3P reduces cell mitosis, proliferation, and drug sensitivity (paclitaxel or cisplatin). The gene discussed is FOXM1; the disease is neoplasm.