it is upregulated in patient samples and cell linesupregulation of REG1CP is an early event during colorectal tumorigenesisREP1CP levels are higher in colon adenomas and dysplastic colon mucosa and in colon cancers compared to normal mucosahigher level is associated with poorer PFSREG1CP activates REG3A by forming an RNA–DNA triplex with the REG3A gene. This evidence concerns the gene REG1CP and colon adenoma.