NFKB1 and neoplasm: it is overexpressed and its expression is connected with tumor degree, transcriptome subtypehigher level is correlated with poor patient outcomesPDIA3P1 expression is associated with EMT, disassembly of ECM, and angiogenesisoverexpression of PDIA3P1 enhanced the migration and invasionHIF-1 is confirmed to directly bind to the PDIA3P1 promoter region and activate its transcriptionPDIA3P1 functions as a ceRNA by sponging miR-124-3p to modulate RELA expression and activate the downstream NF-κB pathway