it is upregulated in patient sampleshigher expression is associated with a larger tumor size, advanced pathological stagehigher expression is associated with shorter OS timeknockdown of DUXAP8 inhibits cell proliferation and promotes apoptosisDUXAP8 regulates cell proliferation partly through downregulation CDKN1A and KLF2. The gene discussed is DUXAP8; the disease is neoplasm.