it is overexpressed in patient tissues and cell linesknockdown of SDHAP1 induces re-acquirement of chemo-sensitivity to PTX in ovarian cancer cells in vitroSDHAP1 upregulates the expression of EIF4G2 by miR-4465 in a sponging-dependent manner, and by this way, influences chemosensitivity. The gene discussed is EIF4G2; the disease is ovarian carcinoma.