it is upregulated patient tissue and cellsknockdown of ANXA2P2 reduces cell proliferation and aerobic glycolysis and downregulates protein levels of glycolysis markers (GLUT1, HK2, PFK, LDHA)miR-9 has negative correlation with its own ANXA2P2 mRNA targetoverexpression of miR-9 suppresses the cell proliferation and aerobic glycolysis of glioma cells by bind to LDHA 3′UTR. Here, HK2 is linked to glioma.