The murine KrasG12DHif1αKO model of pancreatic cancer exhibits an abundant expression of CCL19, CCL20, CCL21, CXCL12, and CXCL13, all of which mediate Breg migration and infiltration into tumor tissue to promote pancreatic tumorigenesis [118]. Here, CXCL13 is linked to familial pancreatic carcinoma.