For instance, Hsu et al., developed poly(D,L)-lactide-co-glycolide (PLGA) core–shell nanofibers where vancomycin and ceftazidime, two antibiotics, were encapsulated in the shell, and the osteogenic growth factor bone morphogenetic protein 2 (BMP-2) in the core [9], with the aim to avoid infection upon implantation and stimulate osteogenesis. The gene discussed is BMP2; the disease is infection.