HOTAIR and breast cancer: However, a meta-analysis study by Mathias et al. analyzing 31 SNPs in 12 lncRNAs could not find any association for these SNPs with breast cancer susceptibility, including rs920778, rs1899663, rs12826786, and rs4759314 SNPs on the HOTAIR locus and rs217727, rs3741219, rs2107425, and rs2839698 SNPs on the H19 locus [93] likely due to the smaller number of studies included for this analysis.