Figure 3 depicts the network of genes with node sizes according to the number of variants with a p-value < 0.05 in the comparison between controls and DKD patients. CNKSR3 had four of these relevant SNPs, whilst GREM1, EPO, ENTPD8 and SP3 had three relevant variants each (Figure 3). The complete set of SNPs achieving a significant p-value is listed in Supplementary Table S1. The gene discussed is ENTPD8; the disease is diabetic kidney disease.