SPHK1 and Parkinson disease: SPHK1 SNP rs2247856 (OR = 0.65, 95% CI = 0.53–0.80, p = 4.35 × 10–5) and FYN SNP rs7772036 (OR = 0.72, 95% CI = 0.61–0.85, p = 9.74 × 10–5) were also associated with PD.