The aim of the study was to determine whether the polymorphism of the adiponectin 11391 G / A gene (rs17300539), which is related to higher body mass index (BMI), an increased risk of insulin resistance, and type 2 diabetes (T2D), influences also to the occurrence of the metabolic syndrome and its components in PCOS patients. This evidence concerns the gene ADIPOQ and polycystic ovary syndrome.