TNFRSF19 and chronic kidney disease: Figure 2 shows regional association plots for IDO activity, eGFR, and CKD of TNFRSF19 ± 100 kb (13q12.12) with the LD block structure. Five SNPs (rs76318819, rs117150322, rs180794424, rs148054567, and rs143600269) plotted were significantly associated with both IDO activity and eGFR. Among them, rs117150322 and rs180794424, rs148054567 and rs143600269 were included in the same LD block. Rare variants passing the significant threshold of 1 × 10−5 are shown in Table S1.