COL4A1 and migraine disorder: Additional forms of COL4A1 mutations include infantile hemiparesis, epileptic seizures, migraine with aura, single or recurrent intracerebral hemorrhages, ocular symptoms (tortuous retinal vessels, congenital cataract, an anomaly of the anterior segment of the eye of the Axenfeld-Rieger type), less often with muscle spasms [76].