Meanwhile, some DEGs were found to be associated with some cancer or cancer pathway, like “pathways in cancer” (PATH:05200), “small cell lung cancer” (PATH:05222), “renal cell carcinoma” (PATH:05211), “pancreatic cancer” (PATH:05212), “bladder cancer” (PATH:05219), which further suggested that SPP-0.7A has antitumor activity. Here, HM13 is linked to hereditary clear cell renal cell carcinoma.