Keyword frequency analysis showed that the 10 most frequently used keywords were ‘asthma’, ‘allergy’, ‘child(ren)’, ‘IgE’, ‘(allergic) rhinitis’, ‘epidemiology’, ‘food allergy’, ‘(allergic) contact dermatitis’, ‘psoriasis’, ‘cytokines’, and ‘pruritus (itch)’ (Figure 2A). Here, IGHE is linked to allergic disease.