IL2 and juvenile idiopathic arthritis: The immunogenic mechanism of JIA is believed to be mediated by chemokines that selectively attract Type 1 Helper (Th1) T-cells, resulting in the cell mediated production of proinflammatory cytokines such as interleukin-2 (IL-2), interferon-gamma and tumour necrosis factor-alpha (TNF-alpha) [2].