By inducing upregulation of IFNγ regulated molecules such as GBP5, STAT1 expression can be considered to play a role in predicted activation of IFNγ along with other immune response molecules associated with parasitic infection such as IIGP1, GBP2, GBP5, IRGM1 and IFI16. Activation of IFNγ can also be attributed to the detection of upregulated gene expression of Lymphocyte antigen 6 complex (LY6C), an antigen indicating the presence of inflammatory monocytes. This evidence concerns the gene STAT1 and parasitic infectious disease.