CD4 and infection: The entry of the virus and the induction of an effective infection in the cells are promoted by the action of different elements such as the presence of CD4, the chemokine receptor CXC 4 (CXCR4), and the chemokine receptors 3 and 5 (CCR3 and CCR5) mediated by protein kinase C (PKC) coreceptors, in addition to processes such as intracellular calcium secretion [52].