As a result of this lower number of CD49d molecules in SD patients, together with the same levels of bound NTZ in both groups, the percentage of CD49d saturation was higher in SD patients compared with EID patients (CD4+ CD49d% saturation: 72.31 vs. 63.82; CD8+ CD49d% saturation: 68.97 vs. 55.91; CD19+ CD49d% saturation: 73.74 vs. 58.30) (Figure 3d). The gene discussed is ITGA4; the disease is Salla disease.