Noteworthy, this miRNA set also regulates important AMD-related genes such VEGF-A, PDGFA and PDGFRA involved in VEGF-signaling pathway, ECM-receptor interaction, cytokine-receptor interaction and cell cycle (Supplementary Figures S2–S6 and Supplementary Table S3). The gene discussed is PDGFA; the disease is age-related macular degeneration.