Sharma et al. reported that both CD14+ monocytic and CD14– granulocytic MDSCs expressed PD-L1 and PD-L2 (~2-fold greater in the latter type of cells); granulocytic MDSCs may suppress tumor-reactive CD8+ T cells in metastatic pelvic lymph nodes [88]. The gene discussed is PDCD1LG2; the disease is neoplasm.