The absolute counts of CD3+ (mean = 866; SD ± 345.5) and CD8+ T cells (mean= 221.1; SD ± 130.4) in COVID-19 patients were significantly decreased compared to heathy controls (CD3 + mean 1401; SD ± 43.6), p = 0.05, (CD8+ mean 594.8; SD ± 260.1), p = 0.01. This evidence concerns the gene CD8A and COVID-19.