NPPB and hydrops fetalis: It is also important to note that CA-related HF patients were in rather advanced disease stages when compared to controls, as documented by higher NT-proBNP levels (median NT-proBNP in pg/mL: 3002.0 [1282.5, 7453.0] in CA patients vs. 452.0 [143.9, 1380.0] in non-CA patients, p < 0.001).