On univariate analysis, the presence of bone marrow involvement (p = 0.028), the presence of pleural effusion (p < 0.001), Hb-level (p = 0.039), HIV-status (p = 0.036), and treatment response (p < 0.001) were predictive of progression-free survival (see Table 2). This evidence concerns the gene GSTM1 and Pleural effusion.