CX3CR1 and atherosclerosis: An experimental report demonstrated that the expression of the chemokine CX3CL1 was selectively upregulated in the aorta of Ldlr−/− mice fed a high-cholesterol diet compared with other lymphoid tissues, and that the adoptive transfer of its counterreceptor CX3CR1-transduced Tregs promoted their migration to the atherosclerotic lesions and reduced atherosclerosis development, although CX3CR1 is mainly expressed on Ly6C+ monocytes and its endogenous expression on Tregs is relatively low [82].