A 2011 study (see [75]) showed a relationship between the DRD2 polymorphism (rs 1800497) and the development of alexithymia, which is associated with difficulties in awareness and self-regulation of emotions [75,78,79] and it seems that this trait could be related to the personality trait studied by us, which is “self-directed, including self-acceptance”. The gene discussed is DRD2; the disease is alexithymia.