CXCL1 and infection: For example, in vitro, it was found to inhibit the growth of Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus faecalis for as long as 2 h of incubation, through the induction of C-C motif chemokine ligands 3 and 5 and C-X-C motif chemokine ligand 1 [55], and in a study in dogs, PRP activated by calcium chloride showed antimicrobial activity against infection by methicillin-resistant Staphylococcus aureus and this was associated with better re-epithelisation and granulation tissue formation improving the healing of the infected wounds [56].