To unequivocally determine the relationship between various parameters that describe PVL channels and clinically significant hemolysis, it would be necessary to correlate morphologies of PVL channels of various patients with this pathology with levels of markers of hemolysis such as lactate dehydrogenase, haptoglobin, free hemoglobin, and reticulocytes. Here, HP is linked to periventricular leukomalacia.