The prevention of Her2-driven breast carcinogenesis by Rlip deficiency [50] and similarities in the effects of AA and Rlip-LNA lead us to a provocative possibility that a relative deficiency of Ω-6 essential fatty acids predisposes to Her2-positive breast cancer and that their supplementation could be preventative. The gene discussed is ERBB2; the disease is hyperinsulinemic hypoglycemia, familial, 4.