MUC5AC and adenocarcinoma: Mucinous HPV-associated adenocarcinoma is subtyped into mucinous, not otherwise specified (NOS) adenocarcinoma, intestinal adenocarcinoma (goblet or enteroendocrine cell differentiation in 50% of the tumor), signet-ring cell adenocarcinoma (non-cohesive cells with a signet-ring morphology and cytoplasmic mucin), and invasive stratified mucin-producing carcinoma [50].