Many studies showed a clear link between CCR5 and CCR5 ligands polymorphism or differential gene signature and several cancer diseases, among them: prostate cancer, breast cancer, glioblastoma, myeloid leukemia, pancreatic adenocarcinoma, Non-Small Cell Lung Cancer (NSCLC), metastatic melanoma, metastatic colorectal cancer and others [98,99,101,102,103,104,105,106,107,108,109,110,111,112,113,114,115,116,117,118,119,120,121,122,123,124,125,126,127,128]. Here, CCR5 is linked to metastatic colorectal cancer.