Additionally, Uziel et al. [86], using medulloblastoma cells from Ink4c −/−; Ptch1 +/− and Ink4c −/−; p53 −/− genetically modified mice versus mature mice, identified many deregulated miRNAs: 26 upregulated and 24 downregulated. The gene discussed is CDKN2C; the disease is medulloblastoma.