RASGRP3 and medulloblastoma: In 2012, it was agreed during an international meeting that medulloblastoma has four distinctive molecular subgroups named: Wingless (WNT-good prognosis), Sonic Hedgehog (SHH-intermedia prognosis), Group 3 (Grp3-bad prognosis) and Group 4 (Grp4-intermedia prognosis) [49].